KNOXVILLE, TN - September 13, 2025 - Quarterback Joey Aguilar #6 of the Tennessee Volunteers during the game between the Georgia Bulldogs and the Tennessee Volunteers at Neyland Stadium in Knoxville, TN. Photo By Andrew Ferguson/Tennessee Athletics
Here are my SEC game predictions for Week 5 of the 2025 season, both straight-up and against the spread.
I’ve also included this week a complete review of the first 4 weeks of predictions that I’ve shared on-air in various settings.
Check back here on my blog page within the SportsTalk Show Page for weekly picks.
Vince’s Predictions
Week 4: 9-1 straight-up & 5-5 spread
Season: 44-9 straight-up & 30-23 spread
Week 5
SATURDAY, SEPTEMBER 27
#22 Notre Dame (1-2) at Arkansas (2-2, 0-1 SEC)
Fayetteville, Ark. • Reynolds Razorback Stadium (76,000)
Series: First Meeting
Noon ET • ABC
SiriusXM: 85
Point Spread: Notre Dame -4
Vince’s Pick with the spread: Notre Dame
Vince’s Score Prediction: Notre Dame 38 Arkansas 28
Utah State (3-1) at #18 Vanderbilt (4-0, 1-0 SEC)
Nashville, Tenn. • FirstBank Stadium (35,000)
Series: First Meeting
12:45pm ET • SEC Network
SiriusXM: 106 / 190
Point Spread: Vanderbilt -22.5
Vince’s Pick with the spread: Vanderbilt
Vince’s Score Prediction: Vanderbilt 43 Utah St. 20
#4 LSU (4-0, 1-0 SEC) at #13 Ole Miss (4-0, 2-0 SEC)
Oxford, Miss. • Vaught-Hemingway Stadium (64,038)
Series: LSU leads, 64-42-4
Last: LSU, 29-26 OT (2024 at Baton Rouge)
3:30 p.m. ET • ABC
SiriusXM: 161/191 – 84
Point Spread: Ole Miss -1.5
Vince’s Pick with the spread: Ole Miss
Vince’s Score Prediction: Ole Miss 30 LSU 27
(RV) Auburn (3-1, 0-1 SEC) at #9 Texas A&M (3-0, 0-0 SEC)
Bryan – College Station, Texas • Kyle Field (102,733)
Series: TAMU leads, 8-7
Last: AU, 43-41 4OT (2024 at Auburn)
3:30 p.m. ET • ESPN
SiriusXM: 162/192 – 81
Point Spread: Texas A&M -6.5
Vince’s Pick with the spread: Texas A&M
Vince’s Score Prediction: Texas A&M 27 Auburn 20
#15 Tennessee (3-1, 0-1 SEC) at (RV) Mississippi State (4-0, 0-0 SEC)
Starkville, Miss. • Davis Wade Stadium at Scott Field (60,311)
Series: UT leads, 30-16-1
Last: UT, 33-14 (2024 at Knoxville)
4:15 p.m. ET • SEC Network
SiriusXM: 145 – 106/190
Point Spread: Tennessee -8.5
Vince’s Pick with the spread: Tennessee
Vince’s Score Prediction: Tennessee 38 Miss State 24
UMass (0-3) at #20 Missouri (4-0, 1-0 SEC)
Columbia, Mo. • Faurot Field (57,321)
Series: MIZ leads, 1-0
7:30 p.m. ET • ESPNU
SiriusXM: 161 / 191
Point Spread: Missouri -44.5
Vince’s Pick with the spread: Missouri
Vince’s Score Prediction: Missouri 56 UMass 0
#17 Alabama (2-1, 0-0 SEC) at #5 Georgia (3-0, 1-0 SEC)
Athens, Ga. • Dooley Field at Sanford Stadium (93,033)
Series: UA leads, 44-26-4
Last: UA, 41-34 (2024 at Tuscaloosa)
7:30 p.m. ET • ABC
SiriusXM: 81 – 84
Point Spread: Georgia -2.5
Vince’s Pick with the spread: Georgia
Vince’s Score Prediction: Georgia 31 Alabama 24
Kentucky (2-1, 0-1 SEC) at South Carolina (2-2, 0-2 SEC)
Columbia, S.C. • Williams-Brice Stadium (77,559)
Series: SC leads, 21-14-1
Last: SC 31-6 (2024 at Lexington)
7:45 p.m. ET • SEC Network
SiriusXM: 374 – 106/190
Point Spread: South Carolina -6.5
Vince’s Pick with the spread: Kentucky
Vince’s Score Prediction: South Carolina 20 Kentucky 17
Open Date: Florida (1-3, 0-1 SEC); Oklahoma (4-0, 1-0 SEC); Texas (3-1, 1-1 SEC).
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Vince’s Predictions
Week 3: 10-2 straight-up & 6-6 spread
Season: 35-8 straight-up & 25-18 spread
Week 4
SATURDAY, SEPTEMBER 20
Arkansas (2-1, 0-1 SEC) at Memphis (3-0)
Point Spread: Arkansas -7.5
Vince’s Pick with the spread: Memphis
Vince’s Score Prediction: Arkansas 38 Memphis 31
UAB (2-1) at 15 Tennessee (2-1, 0-1 SEC)
Point Spread: Tennessee -39.5
Vince’s Pick with the spread: Tennessee
Vince’s Score Prediction: Tennessee 63 UAB 17
Tulane (3-0 at 13 Ole Miss (3-0, 2-0 SEC)
Point Spread: Ole Miss -11.5
Vince’s Pick with the spread: Ole Miss
Vince’s Score Prediction: Ole Miss 45 Tulane 24
22 Auburn (3-0, 0-0 SEC) at 11 Oklahoma (3-0, 0-0 SEC)
Point Spread: Oklahoma -6.5
Vince’s Pick with the spread: Auburn
Vince’s Score Prediction: Oklahoma 20 Auburn 17
Northern Illinois (1-1) at Mississippi State (3-0, 0-0 SEC)
Point Spread: Miss State -21.5
Vince’s Pick with the spread: Miss State
Vince’s Score Prediction: Miss State 56 Northern Illinois 7
South Carolina (2-1, 0-1 SEC) at 23 Missouri (3-0, 0-0 SEC)
Point Spread: Missouri -11.5
Vince’s Pick with the spread: Missouri
Vince’s Score Prediction: Missouri 34 South Carolina 20
Florida (1-2, 0-1 SEC) at 4 Miami (3-0)
Point Spread: Miami -7.5
Vince’s Pick with the spread: Miami
Vince’s Score Prediction: Miami 27 Florida 13
Georgia State (1-2) at 20 Vanderbilt (3-0, 1-0 SEC)
Point Spread: Vanderbilt -26.5
Vince’s Pick with the spread: Vanderbilt
Vince’s Score Prediction: Vanderbilt 42 Georgia St. 14
SE Louisiana (2-1) at 3 LSU (3-0, 1-0 SEC)
Point Spread: LSU -38.5
Vince’s Pick with the spread: SE Louisiana
Vince’s Score Prediction: LSU 38 SE Louisiana 0
Sam Houston State (0-3) at 8 Texas (2-1, 0-0 SEC)
Point Spread: Texas -39.5
Vince’s Pick with the spread: Sam Houston St.
Vince’s Score Prediction: Texas 30 Sam Houston St. 3
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Vince’s Predictions
Week 2: 13-2 straight-up & 9-6 spread
Season: 25-6 straight-up & 19-12 spread
Week 3
SATURDAY, SEPTEMBER 13
Wisconsin (2-0) at Alabama (1-1, 0-0 SEC)
Point Spread: Alabama -21
Vince’s Pick with the spread: Wisconsin
Vince’s Score Prediction: Alabama 38 Wisconsin 20
Oklahoma (2-0, 0-0 SEC) at Temple (2-0)
Point Spread: Oklahoma -22.5
Vince’s Pick with the spread: Oklahoma
Vince’s Score Prediction: Oklahoma 49 Temple 7
South Alabama (1-1) at Auburn (2-0, 0-0 SEC)
Point Spread: Auburn -24.5
Vince’s Pick with the spread: Auburn
Vince’s Score Prediction: Auburn 35 South Alabama 10
Georgia (2-0, 0-0 SEC) at Tennessee (2-0, 0-0 SEC)
Point Spread: Georgia -4
Vince’s Pick with the spread: Tennessee
Vince’s Score Prediction: Georgia 27 Tennessee 24
UL-Lafayette (1-1) at Missouri (2-0, 0-0 SEC)
Point Spread: Missouri -27
Vince’s Pick with the spread: Missouri
Vince’s Score Prediction: Missouri 56 UL-Lafayette 14
UTEP (1-1) at Texas (1-1 0-0 SEC)
Point Spread: Texas -40.5
Vince’s Pick with the spread: Texas
Vince’s Score Prediction: Texas 49 UTEP 7
Alcorn State (0-2) at Mississippi State (2-0, 0-0 SEC)
Point Spread: Miss State -43.5
Vince’s Pick with the spread: Miss State
Vince’s Score Prediction: Miss State 52 Alcorn St. 3
Arkansas (2-0, 0-0 SEC) at Ole Miss (2-0, 1-0 SEC)
Point Spread: Ole Miss -6.5
Vince’s Pick with the spread: Ole Miss
Vince’s Score Prediction: Ole Miss 49 Arkansas 35
Vanderbilt (2-0, 0-0 SEC) at South Carolina (2-0, 0-0 SEC)
Point Spread: South Carolina -3.5
Vince’s Pick with the spread: South Carolina
Vince’s Score Prediction: South Carolina 24 Vanderbilt 17
Eastern Michigan (0-2) at Kentucky (1-1, 0-1 SEC)
Point Spread: Kentucky -24.5
Vince’s Pick with the spread: Kentucky
Vince’s Score Prediction: Kentucky 31 Eastern Michigan 6
Florida (1-1, 0-0 SEC) at LSU (2-0, 0-0 SEC)
Point Spread: LSU -7
Vince’s Pick with the spread: LSU
Vince’s Score Prediction: LSU 34 Florida 15
Texas A&M (2-0, 0-0 SEC) at Notre Dame (0-1)
Point Spread: Notre Dame -6.5
Vince’s Pick with the spread: Notre Dame
Vince’s Score Prediction: Notre Dame 27 Texas A&M 20
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Vince’s Predictions
Week 1 & Season: 12-4 straight-up & 10-6 spread
Week 2
SATURDAY, SEPTEMBER 6
San Jose State (0-1) at Texas (0-1, 0-0 SEC)
Point Spread: Texas -35.5
Vince’s Pick with the spread: San Jose St.
Vince’s Score Prediction: Texas 45 San Jose St. 13
Utah State (1-0) at Texas A&M (1-0, 0-0 SEC)
Point Spread: Texas A&M -30.5
Vince’s Pick with the spread: Utah St.
Vince’s Score Prediction: Texas A&M 31 Utah St. 10
Austin Peay (1-0) at Georgia (1-0, 0-0 SEC)
Point Spread: Georgia -45.5
Vince’s Pick with the spread: Georgia
Vince’s Score Prediction: Georgia 63 Austin Peay 3
Ole Miss (1-0, 0-0 SEC) at Kentucky (1-0, 0-0 SEC)
Point Spread: Ole Miss -8.5
Vince’s Pick with the spread: Ole Miss
Vince’s Score Prediction: Ole Miss 45 Kentucky 7
Kansas (1-0) at Missouri (1-0, 0-0 SEC)
Point Spread: Missouri -5.5
Vince’s Pick with the spread: Missouri
Vince’s Score Prediction: Missouri 38 Kansas 31
ETSU (1-0) at Tennessee (1-0, 0-0 SEC)
Point Spread: Tennessee -40.5
Vince’s Pick with the spread: Tennessee
Vince’s Score Prediction: Tennessee 63 ETSU 7
USF (1-0) at Florida (1-0, 0-0 SEC)
Point Spread: Florida -17.5
Vince’s Pick with the spread: Florida
Vince’s Score Prediction: Florida 38 USF 13
Arkansas State (1-0) at Arkansas (1-0, 0-0 SEC)
Point Spread: Arkansas -22.5
Vince’s Pick with the spread: Arkansas
Vince’s Score Prediction: Arkansas 41 Arkansas St. 14
South Carolina State (1-0) at South Carolina (1-0, 0-0 SEC)
Point Spread: South Carolina -42.5
Vince’s Pick with the spread: South Carolina
Vince’s Score Prediction: South Carolina 45 South Carolina St 0
Ball State (0-1) at Auburn (1-0, 0-0 SEC)
Point Spread: Auburn -43.5
Vince’s Pick with the spread: Ball St.
Vince’s Score Prediction: Auburn 49 Ball St. 10
Louisiana Tech (1-0) at LSU (1-0, 0-0 SEC)
Point Spread: LSU -37.5
Vince’s Pick with the spread: LSU
Vince’s Score Prediction: LSU 42 Louisiana Tech 3
Arizona State (1-0) at Mississippi State (1-0, 0-0)
Point Spread: Arizona St. -6.5
Vince’s Pick with the spread: Miss State
Vince’s Score Prediction: Arizona St. 27 Miss State 24
Michigan (1-0) at Oklahoma (1-0, 0-0 SEC)
Point Spread: Oklahoma -5.5
Vince’s Pick with the spread: Michigan
Vince’s Score Prediction: Oklahoma 24 Michigan 23
Vanderbilt (1-0, 0-0 SEC) at Virginia Tech (0-1)
Point Spread: Vanderbilt -1.5
Vince’s Pick with the spread: Vanderbilt
Vince’s Score Prediction: Vanderbilt 20 Virginia Tech 17
UL-Monroe (1-0) at Alabama (0-1, 0-0 SEC)
Point Spread: Alabama -34.5
Vince’s Pick with the spread: Alabama
Vince’s Score Prediction: Alabama 41 UL-Monroe 6
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Week 1
(2024 Record)
THURSDAY, AUGUST 28
Central Arkansas (6-6) at Missouri (10-3, 5-3 SEC)
Point Spread: Missouri -40.5
Vince’s Pick with the spread: Missouri
Vince’s Score Prediction: Missouri 56 Central Arkansas 0
FRIDAY, AUGUST 29
Auburn (5-7, 2-6 SEC) at Baylor (8-5)
Point Spread: Auburn -2.5
Vince’s Pick with the spread: Auburn
Vince’s Score Prediction: Auburn 31 Baylor 21
SATURDAY, AUGUST 30
Syracuse (10-3) at Tennessee (10-3, 6-2 SEC)
Point Spread: Tennessee -13.5
Vince’s Pick with the spread: Tennessee
Vince’s Score Prediction: Tennessee 31 Syracuse 14
Texas (13-3, 7-1 SEC) at Ohio State (14-2)
Point Spread: Ohio State -1.5
Vince’s Pick with the spread: Texas
Vince’s Score Prediction: Texas 20 Ohio State 17
Mississippi State (2-10, 0-8 SEC) at Southern Miss (1-11)
Point Spread: Miss State -13.5
Vince’s Pick with the spread: Miss State
Vince’s Score Prediction: Miss State 38 Southern Miss 24
Toledo (8-5) at Kentucky (4-8, 1-7 SEC)
Point Spread: Kentucky -10.5
Vince’s Pick with the spread: Toledo
Vince’s Score Prediction: Toledo 24 Kentucky 21
Alabama (9-4, 5-3 SEC) at Florida State (2-10)
Point Spread: Alabama -13.5
Vince’s Pick with the spread: Alabama
Vince’s Score Prediction: Alabama 38 Florida St 17
Marshall (10-3) at Georgia (11-3, 6-2 SEC)
Point Spread: Georgia -38.5
Vince’s Pick with the spread: Marshall
Vince’s Score Prediction: Georgia 38 Marshall 3
Alabama A&M (6-6) at Arkansas (7-6, 3-5 SEC)
Point Spread: Arkansas -46.5
Vince’s Pick with the spread: Alabama A&M
Vince’s Score Prediction: Arkansas 59 Alabama A&M 13
Illinois State (10-4) at Oklahoma (6-7, 2-6 SEC)
Point Spread: Oklahoma -36.5
Vince’s Pick with the spread: Oklahoma
Vince’s Score Prediction: Oklahoma 45 Illinois St 7
UTSA (7-6) at Texas A&M (8-5, 5-3 SEC)
Point Spread: Texas A&M -23.5
Vince’s Pick with the spread: Texas A&M
Vince’s Score Prediction: Texas A&M 35 UTSA 10
Charleston Southern (1-11) at Vanderbilt (7-6, 3-5 SEC)
Point Spread: Vanderbilt -38.5
Vince’s Pick with the spread: Charleston Southern
Vince’s Score Prediction: Vanderbilt 37 Charleston Southern 17
Long Island (4-8) at Florida (8-5, 4-4 SEC)
Point Spread: Florida -45.5
Vince’s Pick with the spread: Florida
Vince’s Score Prediction: Florida 49-0
LSU (9-4, 5-3 SEC) at Clemson (10-4)
Point Spread: Clemson -3.5
Vince’s Pick with the spread: LSU
Vince’s Score Prediction: Clemson 28 LSU 27
Georgia State (3-9) at Ole Miss (10-3, 5-3 SEC)
Point Spread: Ole Miss -34.5
Vince’s Pick with the spread: Ole Miss
Vince’s Score Prediction: Ole Miss 63 Georgia St 14
SUNDAY, AUGUST 31
South Carolina (9-4, 5-3 SEC) vs. Virginia Tech (6-7)
Point Spread: South Carolina -7.5
Vince’s Pick with the spread: South Carolina
Vince’s Score Prediction: South Carolina 27 Virginia Tech 13
