It is the sixth time in NFL history that a player had six or more sacks in a single game.

The 32-year-old Mack recorded three of his sacks of Raiders rookie quarterback Aidan O'Connell in third quarter. He had one apiece in the first, second and fourth quarters.

Mack also forced two fumbles with Chargers teammate Austin Johnson recovering one of them.

In addition to his record-setting outing in 1990 against the Seattle Seahawks, Thomas also had six sacks in a 1998 game against the then-Oakland Raiders.

The others who recorded six in a game are "Mean" Fred Dean (for 49ers in 1983), Osi Umenyiora (Giants, 2007) and Adrian Clayborn (Falcons, 2017).

Mack entered the game without a sack this season. He had eight last season in his first campaign with the Chargers.

Mack has 90.5 career sacks in 10 seasons with Oakland (2014-17), the Chicago Bears (2018-21) and Chargers.

In 2016 with the Raiders, Mack was named NFL Defensive Player of the Year. He is a seven-time Pro Bowl selection.

Thomas played 11 seasons for the Chiefs (1989-99) and is a member of the Pro Football Hall of Fame. He racked up 126.5 career sacks, including a career high of 20 in 1990.

Thomas was involved in an auto accident in early 2000 and sustained a spinal cord injury that left him paralyzed from the chest down. Two-plus weeks later, he died from a pulmonary embolism at age 33.

Thomas was inducted into the Pro Football Hall of Fame in 2009.

It was the 14th consecutive regular-season win for the 49ers (4-0) dating back to last season, and the seventh straight game in which they have scored at least 30 points.

McCaffrey rushed for 106 yards on 20 carries and scored three touchdowns, while adding another score on one of his seven receptions for 71 yards.

Brock Purdy scored the final touchdown of the game on a 1-yard run and completed 20 of 21 passes for 283 yards and a 134.6 passer rating. Brandon Aiyuk had six catches for 148 yards for the 49ers.

Josh Dobbs completed 28 of 41 passes for 265 yards and two touchdowns for the Cardinals (1-3).

McCaffrey scored on runs from 1 and 18 yards out to help San Francisco establish a 14-0 lead with 14:14 left in the first half.

The Cardinals' first scoring drive was set up by an 8-yard run by Dobbs on fourth-and-7 from the 49ers' 45-yard line. That led to a 38-yard field goal by Matt Prater with 8:14 remaining in the second quarter.

McCaffrey's third touchdown, a 6-yard reception over the middle, gave the 49ers a 21-3 lead with 5:22 to play in the half. The Cardinals answered with a drive that continued after a 2-yard run on a fake punt by upback Ezekiel Turner from their own 21-yard line.

After moving to the San Francisco 49-yard line, Dobbs connected with rookie wide receiver Michael Wilson for 33 yards and a 16-yard score on back-to-back plays, making it 21-10 with 23 seconds left. It was the first touchdown of Wilson's career.

Wilson scored again with 4:12 in the third quarter on an 8-yard pass from Dobbs, cutting the Cardinals' deficit to 21-16.

After McCaffrey's fourth touchdown that gave the 49ers a 28-16 lead, Arizona drove to the 49ers 35-yard line, but Dobbs was sacked by defensive tackle Javon Hargrave for an 8-yard loss on third-and-10 with 9:22 remaining, ending the threat. San Francisco sealed the game with a 14-play, 77-yard touchdown drive that took 7:14 off the clock.

CeeDee Lamb and Hunter Luepke also scored for Dallas (3-1), whose three victories all have come by 20 points or more. Dak Prescott completed 28 of 34 passes for 261 yards and a touchdown.

Mac Jones completed 12 of 21 passes for 150 yards and two interceptions for New England (1-3). Jones was replaced late in the third quarter by Bailey Zappe, who completed 4 of 9 passes for 57 yards.

Dallas outgained New England 377-253. The Cowboys tallied 22 first downs, compared with 10 for the Patriots.

The Cowboys wasted no time setting the tone. They established a 10-3 advantage at the end of the first quarter and surged to a 28-3 lead by halftime.

Brandon Aubrey started the scoring with a 23-yard field goal for Dallas.

New England pulled even at 3-3 after Chad Ryland made a 29-yard field goal.

Dallas took the lead for good late in the first quarter. Prescott threw a 20-yard touchdown pass to Lamb to finish off a 10-play, 75-yard drive.

The Cowboys' defense notched a touchdown to make it 18-3 early in the second quarter. Defensive end Dante Fowler sacked Jones and forced a fumble, and Vander Esch picked up the ball and ran 11 yards to the end zone for his first career touchdown.

Dallas added a two-point conversion on a trick play as punter Bryan Anger took the snap, pretended to hold it for the extra-point attempt, and then lobbed a pass to defensive lineman Chauncey Golston.

Aubrey made another 23-yard field goal with 4:03 left in the half.

Dallas showcased its defensive prowess once again to go ahead 28-3 with 54 seconds before halftime. Bland jumped in front of a high pass by Jones and sprinted down the field for a 54-yard pick-6.

Aubrey added a 33-yard field goal to make it 31-3 in the third quarter.

Dallas closed out the scoring on Luepke's 3-yard rushing touchdown with 6:38 remaining.

Justin Herbert completed 13 of 24 passes for 167 yards with a touchdown and an interception and added two rushing scores for the Chargers (2-2), who have won two in a row. Herbert stayed in the game after injuring his left (non-throwing) hand during an interception return, wearing a splint on the middle finger.

Mack, meanwhile, fell one sack shy of tying Derrick Thomas' single-game sack record.

Aidan O'Connell made his first NFL start for the Raiders after Jimmy Garoppolo remained in concussion protocol. The rookie from Purdue completed 24 of 39 passes for 238 yards with an interception.

Davante Adams caught eight passes for 75 yards and running back Josh Jacobs caught eight passes for 81 yards while adding 58 yards rushing for the Raiders (1-3).

The Raiders trailed 24-7 at halftime before making a late push. They cut it to 24-10 on a 22-yard field goal by Daniel Carlson with 4:51 in the third quarter, then made it a one-possession game when Jacobs scored on a 1-yard run with 3:59 to play.

For the second week in a row, the Chargers went for it on fourth-and-1 in their own territory late in the game and Herbert was stopped for no gain, giving the Raiders the ball at their 34 with 3:30 left.

Las Vegas reached the 3-yard line, but Asante Samuel Jr. intercepted O'Connell to put the game away.

Los Angeles marched 86 yards on nine plays on the game's opening drive and Herbert capped it with a 12-yard touchdown run for a 7-0 lead. The drive included a 51-yard run by wide receiver Derius Davis.

On the Raiders' second drive, O'Connell scored on a 1-yard sneak with 45 seconds left in the opening quarter to tie the score 7-7.

After a 33-yard field goal by Cameron Dicker gave the Chargers a 10-7 lead, O'Connell was sacked on third-and-6 and fumbled the ball. Chris Rumph II recovered for Los Angeles at the Las Vegas 36.

Los Angeles capitalized five plays later when Herbert connected with Keenan Allen on a 7-yard touchdown to extend the lead to 17-7 with 7:20 left in the half.

Mack had a strip-sack of O'Connell on third down on the next series, and Austin Johnson recovered for the Chargers at the Raiders' 35.

Los Angeles cashed in that turnover as well when Herbert scored on a 1-yard sneak on fourth-and-goal to increase the lead to 24-7 with 3:05 left in the half.

White dropped back in coverage when Miami quarterback Tua Tagovailoa was sacked with 39 seconds left in the third and was shown putting no pressure on his right leg as the play developed.

No one had made contact with White, who fell to the turf in pain and then threw his helmet in frustration.

White, 28, tore his ACL during the 2021 season in a Thanksgiving victory over the New Orleans Saints.

On Sunday, White had three tackles and a pass defense prior to exiting.

In three games prior to Sunday's meeting with the Dolphins, White had nine tackles and an interception. He is in his seventh season with Buffalo.

Higgins, 24, was seen coming in and out of the medical tent in the first half before quickly returning to the game. However, he did not come out of the locker room after halftime.

Before being removed from the game, Higgins caught two balls for 19 yards.

Higgins has caught 227 passes for 3,157 yards and 21 touchdowns in 50 (46 starts) games since being a second-round pick (33rd overall) in the 2020 draft out of Clemson.

Pickett was ruled out, leaving Mitch Trubisky to take over at quarterback for Pittsburgh.

The Steelers were faced with fourth-and-1 from the Houston 33-yard line, trailing 16-6 with 1:16 left in the third quarter. They tried a passing play, the pocket collapsed on Pickett and defensive end Jonathan Greenard recorded the sack, with some of his body weight landing on Pickett's left leg.

Pickett needed help to get off the field, unable to put weight on the left leg.

He was evaluated in the medical tent before walking back to the locker room, no longer limping.

Pickett was 15-for-23 passing for 114 yards and an interception before leaving the game.

The Titans defense held the Bengals to just 211 yards while Ryan Tannehill completed 18 of 25 passes for 240 yards and a touchdown.

One week after gaining just six first downs, the Titans rebounded with a balanced attack against a Bengals defense that wilted in the 85-degree heat with missed tackles and blown assignments.

Joe Burrow was ineffective and off-target for most of the day, finishing 20 of 30 for 165 yards.

The Bengals were held to three points for the second time in four games this season. Adding to Cincinnati's misery was the loss of two players to injury. Tee Higgins suffered a rib injury in the first half and did not return while starting cornerback Cam Taylor-Britt left in concussion protocol in the third quarter and did not return.

Already up 24-3, the Titans opened the third quarter with a 15-play drive that consumed over 10 minutes of the clock, aided by Dax Hill's unsportsmanlike conduct call on third down when it appeared the Bengals' defense was ready to get off the field on a three-and-out.

Joe Mixon was one of Cincinnati's lone bright spots with 67 yards on 14 carries.

The Bengals were off to a promising start when they took the ball and drove right down the field. Ja'Marr Chase and Higgins each had two catches for 26 and 19 yards respectively.

The Bengals drove to the Titans 10, but the Bengals couldn't punch it in. Additionally, Burrow was lucky he didn't get intercepted on second down when Amani Hooker stepped in front of Higgins and nearly picked off a pass that could've resulted in a pick-6 for Tennessee.

The Bengals ran it with Mixon on the next play down to the Titans 3 and had to settle for a 21-yard Evan McPherson field goal.

Mixon was a force in the first quarter, running it five times for 33 yards for a 6.6-yard average.

The Titans started bringing more pressure in the second quarter and got to Burrow, including a sack and two quarterback hits that landed Burrow flat on his back.

It was the fourth field goal for Elliott as Philadelphia (4-0) remained atop the NFC East.

In a seesaw game, the Eagles recovered after surrendering the game-tying touchdown on the final play of regulation.

Sam Howell's 10-yard pass to Jahan Dotson as the game clock hit zeroes, followed by Joey Slye's extra-point conversion, sent the game to overtime.

Washington (2-2) had the ball first in the extra session but Philadelphia forced a punt.

Jalen Hurts converted a fourth-and-1 with a quarterback sneak from midfield and completed an 11-yard pass to D'Andre Swift for another first down before Elliott hit his game-winner.

Hurts completed 25 of 37 passes for 319 yards and two touchdowns, both in the second half to A.J. Brown, who had nine receptions for 175 yards.

The Eagles trailed 17-7 in the first half before scoring 17 straight points.

Howell led Washington with 29 completions in 41 attempts for 290 yards and no interceptions in the turnover-free game. Terry McLaurin had eight receptions for 86 yards.

Philadelphia led 24-17 in the fourth quarter before Washington tied it with a 75-yard drive, fueled by a 15-yard unnecessary roughness call against the Eagles' Terrell Edmunds. Brian Robinson's 15-yard touchdown run tied it with 8:01 left.

The Eagles took a 31-24 lead with 1:43 left as Hurts threw a 28-yard touchdown pass to Brown. But Brown was flagged for taunting after the play, pushing back the Eagles' ensuing kickoff, and the Commanders took advantage.

With Howell completing six passes, Washington drove 64 yards in the final 1:43 of regulation to send the game to overtime.

In the first quarter, both teams scored on their opening possession with look-alike 75-yard drives. Curtis Samuel put Washington up with a 1-yard run on a jet sweep before Swift countered with a 5-yard touchdown carry.

On the Commanders' next possession, they again traveled 75 yards, with 27 coming on a pass to Logan Thomas. Two plays later, Robinson fumbled near the goal line but McLaurin recovered in the end zone to give Washington a 14-7 lead.

Nicholas Morrow had three sacks to lead the Eagles' defense.

Mayfield completed 24 of 31 passes for 246 yards and threw touchdowns of 4 yards to Cade Otton, 1 yard to Trey Palmer and 5 yards to Deven Thompkins.

Saints running back Alvin Kamara made his season debut after serving a three-game suspension for violating the NFL's personal conduct policy and quarterback Derek Carr started despite a sprained AC joint in throwing shoulder sustained a week earlier in a loss at Green Bay.

But the Bucs (3-1) held Kamara to 51 yards on 11 rushes and 33 yards on 13 pass receptions while Carr completed 23 of 37 for 127 yards. New Orleans (2-2) managed just 197 total yards and three field goals by Blake Grupe.

Grupe kicked a 32-yard field goal to pull New Orleans within 14-6 at the end of the third quarter.

Chase McLaughlin's 51-yard field goal pushed the lead to 17-6 with 13:31 left in the game.

Grupe's 44-yarder got the Saints within eight points, but Mayfield's 5-yard touchdown to Thompkins increased the lead to 23-9 with 3:44 left.

After a Carr fumble, McLaughlin kicked a 28-yard field goal to complete the scoring with 2:24 left.

On the first possession of the game Carr passed for 17 yards and Kamara ran for 9 yards, leading to Grupe's 37-yard field goal for a 3-0 lead that held up through the end of the first quarter.

Mayfield's touchdown pass to Otton was the fourth third-down conversion in as many tries during a 17-play, 87-yard drive that gave the Bucs a 7-3 lead.

The Saints stopped a scoring threat when Isaac Yiadom intercepted Mayfield at the Saints 1-yard line in the final minute of the first half. But on the next play Antoine Winfield Jr. forced a fumble by Adam Prentice and recovered the ball at the 6.

Two plays later, Mayfield connected with Palmer with 19 seconds left, increasing Tampa Bay's lead to 14-3 at halftime.

On the same day the Texans (2-2) inducted former star defensive end J.J. Watt into their ring of honor, Houston held the Steelers to 12 first downs and outgained Pittsburgh 451-225. Stroud completed 16 of 30 passes for 306 yards, and Collins racked up seven catches for a career-high 168 yards.

Steelers quarterback Kenny Pickett went 15-of-23 passing for 114 yards and an interception before suffering a left knee injury late in the third quarter. Mitch Trubisky played the rest of the game and could not guide Pittsburgh (2-2) out of its hole.

Najee Harris had 14 carries for 71 yards and a team-high 32 receiving yards on one catch.

The Texans opened the game with a 12-play, 69-yard touchdown drive. Stroud hit Collins from 2 yards out at the 8:55 mark of the first quarter.

Pickett took a deep shot on Pittsburgh's first possession and former Steeler Steven Nelson came down with the interception, returning it 31 yards for Houston.

That set up the first of three field goals for Ka'imi Fairbairn, his 36-yard kick putting Houston up 10-0 before the end of the first quarter.

Fairbairn added a 38-yarder with 12:09 left in the first half, sandwiched between two Pittsburgh three-and-outs.

Pittsburgh's last drive of the half was cut short after tight end Pat Freiermuth was called for offensive pass interference. With less than a minute, Stroud connected with Collins on catch-and-runs of 42 and 15 yards, setting up Fairbairn's 39-yard field goal at the buzzer for a 16-0 halftime lead.

The Steelers gained just 53 yards before halftime. Pittsburgh more than doubled that yardage total with the opening possession of the second half, but a 58-yard drive only yielded Chris Boswell's 35-yard field goal. They added Boswell's 23-yarder to make it 16-6 with 5:47 left in the third.

The Steelers then faced fourth-and-1 at Houston's 33-yard line and tried a pass. The pocket collapsed on Pickett and defensive end Jonathan Greenard recorded the sack. Pickett needed help getting off the field, unable to put weight on his left leg.

The Texans traveled 68 yards in 10 plays and scored on a trick play. Running back Devin Singletary took a pitch right and tossed a 6-yard touchdown to tight end Dalton Schultz with 10:50 left to play.

Stroud dropped a dime to Collins in stride for a 52-yard exclamation point score with 3:39 to play.

The Rams went 75 yards on their overtime drive with Nacua scoring his first career TD on a third-down play. The BYU product made NFL history twice, with his 39 receptions and 501 receiving yards both marking the most in a player's first four career games.

Kyren Williams scored two first-quarter touchdowns for the Rams (2-2) and had 103 yards on 25 carries. Stafford was 27 of 40 passing for 319 yards and one interception with his touchdown as he was hobbled in the second half by a right leg injury. Nacua had nine receptions for 163 yards.

The Colts rallied to tie the game 23-23 with 1:56 remaining on a 5-yard TD pass from rookie quarterback Anthony Richardson to Drew Ogletree, then getting a 2-point conversion on a Michael Pittman Jr. reception. It was Ogletree's first career touchdown.

Richardson was 11 of 25 passing for 200 yards and two TDs in the air, while getting another on a fourth-quarter run after missing last week's victory over the Baltimore Ravens with a concussion.

Zack Moss had 18 rushes for 70 yards and Richardson ran the ball 10 times for 56 yards for the Colts (2-2), who have lost both of their home games this season.

The Rams turned the opening drive of the game into a 7-0 lead on a nine-play 75-yard drive that ended with Williams' first TD. Los Angeles topped that in its second drive, going 94 yards in 10 plays, with Williams scoring another short TD run.

The Rams scored points on each of their first four drives of the game, getting 40-yard and 54-yard field goals from Brett Maher in the second quarter to take a 20-0 lead.

Los Angeles took a 23-0 lead on a 51-yard field goal from Maher with 7:17 remaining in the third quarter before the Colts began their comeback.

Richardson threw a 35-yard TD pass to Mo Alie-Cox with 5:26 remaining in the third quarter for the Colts' first points of the game and got a Moss reception for the 2-point conversion and a 23-8 deficit.

Richardson scored on a 1-yard TD run with 11:45 remaining to pull Indianapolis within one possession at 23-15.

Brandon Stephens, Geno Stone and Kyle Hamilton had interceptions and the Ravens (3-1) limited a Cleveland offense missing Deshaun Watson to 166 total yards. Mark Andrews caught two touchdown passes and Jackson completed 15 of 19 passes for 186 yards.

Watson missed the game with a sore throwing shoulder that he injured during the Week 3 victory over the Tennessee Titans. He attempted to throw before the game before being ruled out.

Fifth-round draft pick Dorian Thompson-Robinson started in Watson's place and was 19-of-36 passing for 121 yards and three interceptions. The former UCLA star appeared too hyped up at the outset and struggled to find a comfort zone in his first NFL start.

Myles Garrett had a sack for the Browns (2-2) to raise his season output to 5.5.

Cleveland converted just 4 of 16 third-down conversions.

The Ravens had 296 total yards against the Cleveland defense that led the NFL in both scoring defense and total defense entering the contest. Andrews had five receptions for 80 yards.

Baltimore received a big break in the opening quarter when Stephens picked off a deflected Thompson-Robinson pass and returned it 52 yards to the Cleveland 10-yard line. On the next play, Jackson ran through a big hole up the middle for a 10-yard scoring run with 6:38 remaining.

First, the Ravens drove 93 yards on eight plays with Jackson capping it with a 3-yard run with 4:18 left in the half. Baltimore later put together a 10-play, 74-yard drive that saw Jackson pinpoint a high pass to the right back corner of the end zone in which Andrews leaped to grab and make it 21-3 with 11 seconds to go in the half.

Stone nabbed an interception with 9:35 remaining in the contest when a heavily pressured Thompson-Robinson badly overthrew Donovan Peoples-Jones. Stone returned it 36 yards to the Cleveland 38. Six plays later, Jackson tossed an 18-yard touchdown pass to Andrews with 5:56 left.

In earning Sean Payton his first win as their coach, the Broncos scored 24 unanswered points to end the game. They tied the score at 28 with 6:55 left when Jonathon Cooper scooped up a fumble by Justin Fields and returned it 35 yards for a touchdown.

That was the first of three big plays for a defense that allowed 70 points last week in a 50-point loss at Miami. The Broncos stopped Khalil Herbert for no gain on fourth-and-1 at the Denver 18 with 2:52 left and then sealed the outcome when Kareem Jackson picked off Fields at the Broncos' 36 with 32 seconds remaining.

Russell Wilson completed 21 of 28 passes for 223 yards and three scores for Denver (1-3). He connected on a 48-yard pass to Marvin Mims Jr. that set up Lutz's go-ahead kick.

The Bears (0-4) wasted a big day from Fields, who was 28-of-35 for 335 yards and four touchdowns. They lost their 14th straight game dating to October 2022.

Denver struck first with Wilson's 18-yard touchdown pass to Jaleel McLaughlin at the 5:08 mark of the first quarter, capping an 84-yard drive that used up more than six minutes. The rest of the half's remainder was all Chicago.

Fields tied the game on the first play of the second quarter, finding DJ Moore for a 29-yard strike. He then cashed in a short field by hitting Cole Kmet on a 22-yard touchdown pass with 11:44 left in the half. The margin grew to 21-7 when he found Kmet again on a 3-yard scoring strike with 6:08 remaining.

The Bears upped their lead to 28-7 with a drive of nearly 9 1/2 minutes on their first possession of the third quarter, Fields throwing to Khalil Herbert for a 2-yard touchdown.

Denver started its rally on its next drive as Brandon Johnson caught a 4-yard scoring pass from Wilson. The quarterback hit Courtland Sutton for a 13-yard TD strike early in the fourth quarter.

Herbert rushed for 103 yards on 18 carries for Chicago and Moore finished with eight receptions for 131 yards in defeat.

Kirk Cousins completed 12 of 19 passes for 139 yards, two touchdowns and two interceptions for Minnesota (1-3). Alexander Mattison led the team with 95 rushing yards on 17 carries.

Safety Sam Franklin Jr. had a 99-yard interception return for the Panthers' lone touchdown. Bryce Young completed 25 of 32 passes for 204 yards for Carolina (0-4).

The Vikings scored 14 unanswered points in the second half to secure their first win.

Minnesota relied on its defense to take its first lead with 3:58 left in the third quarter. Harrison Smith rushed in on a safety blitz, which caused Young to fumble. Linebacker D.J. Wonnum did the rest with 51-yard scoop and score to put the Vikings ahead 14-13.

The Vikings increased their lead to 21-13 as time expired in the third quarter. Jefferson made a leaping catch down the left side of the field for a 30-yard touchdown, which marked his second score of the game and his third of the season.

Carolina marched into the red zone in the final two minutes as it tried to force overtime. Smith sealed the outcome on another safety blitz when he sacked Young on fourth-and-goal to force a turnover on downs.

The Panthers struck first with a defensive touchdown. Cousins tried to fire a pass to wideout K.J. Osborn near the front of the end zone, and Franklin stepped in front of it for his first career interception and sprinted the length of the field.

Carolina made it 10-0 on a 26-yard field goal by Eddy Pineiro early in the second quarter.

The Vikings got on the scoreboard on the next possession. Cousins rolled to his right and found Jefferson in the end zone for a 4-yard touchdown.

Another Panthers interception, this time by linebacker Kamu Grugier-Hill, helped to set up a field goal at the end of the half. Pineiro was good from 56 yards to make it 13-7.

Allen completed 21 of 25 passes for 320 yards while also rushing for a score. Diggs finished with six catches for 120 yards for Buffalo (3-1), which racked up 414 yards of total offense.

One week after totaling four touchdowns (two rushing, two receiving), Miami rookie De'Von Achane ran for two more TDs and 101 yards on just eight carries.

Tua Tagovailoa threw for 282 yards, one touchdown and one interception on 25-for-35 passing for the Dolphins (3-1), who were held in check after scoring 70 points against the Denver Broncos in Week 3.

Tagovailoa's 11-yard scoring strike to Braxton Berrios with 9:30 left in the third quarter pulled Miami within 31-20. The Dolphins then failed a two-point conversion, and the Bills took command of the game from there.

Buffalo rifled off 17 unanswered points, getting Tyler Bass' 33-yard field goal and Diggs' 13-yard TD catch before Allen scampered into the end zone from 11 yards out with 14:55 left in the contest.

Diggs made an incredible 55-yard catch-and-run touchdown, in which he spun out of the grasp of a pair of defenders and ran down the left sideline for a 28-14 lead with 2:58 left in the first half.

Bass added a 53-yard field goal just more than a minute later to send the Bills into the break with a 31-14 advantage.

After Allen capped the opening drive of the game with an 18-yard touchdown pass to Gabe Davis, Miami answered with a seven-play, 77-yard drive that ended with Achane's 3-yard rushing score.

James Cook then put Buffalo up 14-7 with 1:10 left in the first quarter, plunging into the end zone from the 1.

Achane scored again, this time on a 10-yard run, to make it 14-14 with 12:47 remaining in the second quarter.

Four plays after a 43-yard defensive pass interference penalty, Allen found Diggs for an 11-yard TD to put Buffalo back in front.

Nacua set the record when he caught a 26-yard pass over the middle from Matthew Stafford.

The pass was high, but Nacua reached for it, then tipped the ball to himself to secure the catch.

The play helped to set up a touchdown run by Kyren Williams for his fifth score of the season and a 7-0 Rams lead.

Nacua, 22, was taken by the Rams in the fifth round of the 2023 NFL Draft.

Entering Sunday's game at Indianapolis, Nacua led the Rams in both receptions (30) and yards (338) to help fill the void left by the injury absence of All-Pro Cooper Kupp.

Carr was listed as questionable following the AC joint sprain he sustained in last week's loss to the Green Bay Packers. He participated in practice on Friday, the same day his coach commented on his availability.

"Can he go out and execute his job?" New Orleans coach Dennis Allen said. "That's really all this is."

Multiple media outlets reported that the Saints (2-1) have been preparing for Carr to start, barring any setbacks Sunday. If Carr is unable to go, Jameis Winston will start in his place against the Buccaneers (2-1).

In last Sunday's 18-17 loss to the Green Bay Packers, Carr landed hard on his right shoulder when he was sacked by linebacker Rashan Gary on a third-down play with 10:39 left in the third quarter.

Carr completed 13 of 18 passes for 103 yards and a touchdown. The Saints led 17-0 when Carr was hurt before Green Bay scored 18 unanswered points.

Winston completed 10 of 16 passes for 101 yards.

The Saints' listed inactives for Sunday included cornerback Paulson Adebo, safety Jordan Howden, quarterback Jake Luton, tight end Foster Moreau, wide receiver A.T. Perry, defensive end Kyle Phillips and guard Cesar Ruiz.

The Buccaneers listed cornerback Jamel Dean, linebacker SirVocea Dennis, tight end Payne Durham, defensive lineman Calijah Kancey, cornerback Derrek Pitts, tackle Brandon Walton and linebacker Markees Watts as inactive.

The move comes on the heels of Claypool venting his frustration with how he is being used in the offense.

Claypool, acquired in a trade last November with the Pittsburgh Steelers, has just four catches for 51 yards and a touchdown in three games this season. He is playing in the final season of his rookie contract.

The 2020 second-round pick has 171 catches for 2,235 yards and 13 touchdowns in 49 games (32 starts) with the Steelers and Bears.

Bears wide receiver Equanimeous St. Brown was listed as active for the first time this season.

In addition to Claypool, the Bears (0-3) made the following players inactive for Sunday's game: running back D'Onta Foreman, defensive backs Eddie Jackson and Jaylon Johnson and quarterback Nathan Peterman.

As for the Broncos (0-3), safeties Justin Simmons and JL Skinner, linebackers Frank Clark and Josey Jewell, defensive end Ronnie Perkins, defensive tackle Mike Purcell and center Alex Forsyth were ruled inactive.

He'll be filling in for veteran starter Jimmy Garoppolo, who is in the concussion protocol and has been ruled out.

The Raiders (1-2) opted for O'Connell over 37-year-old Brian Hoyer, who has not started and won a game since Oct. 2, 2016, as a member of the Chicago Bears.

O'Connell will be making his NFL regular-season debut. In the preseason, he threw for 482 yards and three touchdowns with no interceptions.

He was a fourth-round pick (No. 135 overall) in the 2023 NFL Draft. In four seasons at Purdue, he completed 66.7 percent of his passes for 9,219 yards and 65 touchdowns against 30 interceptions.

The Raiders signed Garoppolo to a three-year, $72.75 million contract in the offseason to replace longtime starter Derek Carr.

Las Vegas also ruled cornerback Nate Hobbs out for Sunday. For the Chargers, center Corey Linsley is out due to an illness.